REPLACEMENT CONTROLS FOR:

B. Braun 150L controller
NBS 100L bioreactor
Sartorius Biostat D 250L controls
Unsupported bioreactor controller
B Braun Biostat B 8 liter image courtesy of FedEquip
NBS New Brunswick Bioflo 3000 fermentor image courtesy of FedEquip
NBS New Brunswick Bioflo 4500 bioreactor control system image courtesy of FedEquip
Replacement controller for B Braun/Sartorius Biostat C bioreactor
*Certain images courtesy of Federal Equipment Company

When NBS Eppendorf and B. Braun Sartorius stopped supporting your systems…

Replacement bioreactor control system for stainless steel fermenter

You started scanning the used market for boards and parts to keep your equipment up and running.

ILS has a better solution. One that lets you keep your existing glass and stainless vessels and replace the controller with an open, adaptable system for a fraction of the cost of a new system.

15L glass bioreactor vessel

The AFC 900 series is a drop-in replacement controller for any glass reactor system, including jacketed reactors, but with direct analog and digital sensor support, scales, MODBUS, and more.

The AFC 2000 series is designed for larger SIP/CIP systems. Let ILS customize your controls with open, non-proprietary, quality components. You decide what to update. ILS will customize the system to meet your current and future requirements for 10% to 20% of the cost of a new system.

New Life for an Old Reactor

See how ILS updated a 30+ year old stainless SIP reactor and helped a pharmaceutical company increase batch consistency.
READ CASE STUDY >

The Process

  1. 1. Assessment

    ILS will work with customers to evaluate the current state of the vessel and existing control elements. In some circumstances, ILS can reuse existing control elements such as motor drives, transducers, instruments, valves, etc.

  2. 2. Design

    Customer can choose to replicate the existing capabilities but often upgrades instrumentation, control elements and functionality, if desired. The may include adding a pressure control valve, supporting new instrumentation such optical DO and adding additional gas flow controllers. ILS will work with the customer to design a system, that meets their needs today with room to grow into the future.

  3. 3. Implementation

    ILS will work with the customer and local maintenance/electrical personnel to install the new control system. On-site testing typically involves run-throughs with water and fermentation.

  4. 4. Support

    Typically, new installations require a few runs to “shake-out” the system. This involves monitoring process data and working with operational personnel to discover and remedy any issues. Most often, these issues are programming-related and can be resolved by ILS through remote access to the system.

Before & After Controller Replacement

  • NEW AFC 928: Micro pumps replace syringe pumps for very low flow applications with precise control down to 0.05 ml/hr
  • NEW AFC 928: 3 full size and 4 micro Watson Marlow variable speed pump heads per reactor
  • AFC 927/928 controls two reactors, AFC 917 controls a single reactor
  • Standard 500 W stirrer motor (~0.5 HP) supports 2 — 15L reactors
  • Controls a variety of glass reactors including Applikon, Sartorius, Broadley James, New Brunswick and Millipore Single-Use
  • Flexible design supports either heat blanket or jacketed reactors with water box
  • Cell Culture or Microbial applications with same configuration
  • Gas mixing supports one to six gas flow controllers for multiple sparging and headspace ports
  • Open, non-proprietary design allows for easy customization. Customers have access to the controller software and detailed wiring diagram.

    • Learn more about the AFC 900

  • AFC 2000 has been applied to a variety of steel reactors from 10 liter Sartorius systems to 1500 liter New Brunswick reactors.
  • Controls a wide range of reactors including Applikon, Sartorius, Broadley James, New Brunswick, Millipore Single-Use, and more.
  • Lower cost alternative to buying completely new reactors.
  • Control panel and modular design options are available to suit your needs, both large and small.
  • Modern control with enhanced instrument integration.
  • Gas mixing supports one to six gas flow controllers for multiple sparging and headspace ports.
  • Open, non-proprietary design allows for easy customization. Customers have access to the controller software and detailed wiring diagram.

    • Learn more about the AFC 2000

Top Controller Brands That We Replace

This is a short list of brands, makes and models of bioreactor controls that we replace. Just because they’re on this list does not mean they’ve been discontinued by their manufacturer. Some of them are just difficult or expensive to support. If you have a question about whether ILS can build a replacement solution around your controller, contact our technical support department.
  • Eppendorf NBS New Brunswick Scientific BioFlo 3000, BioFlo 3600, BioFlo 4500, BioFlo 5000
  • Sartorius B. Braun Biostat B, Biostat B Plus, Biostat C, Biostat C Plus, Biostat D, Biostat Quads, Biostat Twins

Our Design Principles

ils design principles cab staff
  • Use open, non-proprietary, readily available, quality components
  • Design our equipment to be serviceable by the customer
  • Design solutions that are tailored to the customer’s needs
  • Customize software & interfaces to match the customer’s requirements
  • Provide complete documentation & source code
  • Provide ongoing, personal support & technology upgrades for our customers and products

Save Time

Stop spending hours searching eBay and other sites for bioreactor replacement parts.

Save Money

Stop buying up lots of broken controllers in the hope that a few good parts will keep your outdated and unsupported equipment running just a little longer.

Reclaim Space

Get rid of that boneyard of spares and get back to work creating product.
Live long and prosper.

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